| C-LAB | Cooperative Computing & Communication Laboratory | Joint research and development laboratory operated by Atos and Paderborn University | | since 1986 | |
| L-LAB | Research Centre for Lighting Engineering and Mechatronics | Public Private Partnership between Hella KG Hueck & Co., Hamm-Lippstadt University of Applied Sciences and Paderborn University | | since 2000 | |
| s-lab | Software Quality Lab | Competence Centre for Software Quality | | since 2005 | |
| DMRC | Direct Manufacturing Research Center | Consortium of industry partners and Paderborn University | | since 2008 | |
| it's owl | BMBF-Leading-Edge Cluster „Intelligente Technical Systems OstWestfalenLippe“ | Technology network it's OWL is an alliance of 180 businesses, universities, research institutes and other partners | | since 2012 | |
| SICP | Software Innovation Campus Paderborn | Cooperation of Paderborn University with the Fraunhofer Institute IEM and regional partners | | since 2013 | |
